Any undergraduate studying biochemistry will be taught that the structure of biological molecules determines their function. This is true. For example, enzymes (nature’s catalysts) have active sites which are adapted to complement the shape of the molecules they bind to. However, biological macromolecules like proteins are constantly in motion – shaking, wobbling and vibrating. This mobility is also critical to function, a point Professor David Timson illustrated with examples from his own research on proteins. Mutations can result in changes to how proteins fold and move – events which can result in genetic diseases. Professor Timson aimed in this lecture to demonstrate that protein structure and mobility determine biological function.