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Dr Dipak K Sarker

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Dr Dipak K Sarker

Dipak Sarker is best defined as a physicist and material scientist with an interest in processing, manufacturing and fabrication of novel and commercial products. He developed this interests from his studies in chemistry, engineering and physics and large company employment experience, with manufacturing being the common link through much of his teaching, research, consultancy and fundamental scientific interests. At the heart of his work is a profound interest in nanotechnology, nanomaterials and the nano-scale. He works alongside designers, process specialists, formulators and theoreticians to achieve the desired research outcome, or profile of concept and commercial products and routes to manufacture. In an academic context, he works routinely with chemists, chemical engineers, clinicians, biologists, pharmacists, engineers and physicists but also in terms of commercial activity alongside business advisors and legal experts.

He sits on a number of scientific journal editorial boards, acts as a reviewer for about 20 scientific periodicals and 3-4 funding bodies, has written many scientific articles, presented his work internationally and nationally and written several books and a number of book chapters. At any point in time he has a number of visiting scientists, post-docs and doctoral researchers under his supervision and is the academic lead in a number of collaborative industrial projects.

Dipak-Sarker

How I like to teach

I am an academic at the 91¶¶Òõ having previously work at the ÉNS in Paris, INRA in France, The Max-Plank Institute in Berlin and the University of East Anglia. I have expertise in subjects ranging from industrial engineering to cell biophysics and on to methods of chemical analysis. I teach aspects of industrial manufacture, physics, physical chemistry, pharmaceutical chemistry, pharmaceutical technology, analytical chemistry, medicine formulation, radiochemistry, mathematics and statistics, biotechnology, quality control, drug product regulation and product licensing.

I try to engage students by making my lectures interactive, animated and frequently make use of models, props and demonstrations. I think my students think they learn best when they are shown how to access the best information and are taught the study skills needed to achieve this. I expect all students to do their best and use both natural and acquired skills to find the best route to solve a problem. I use blended learning, tutorials and seminars, flipped learning, modern educational psychology, innovative pedagogic practices, diverse media and published material, current educational and research information and real-world examples to populate my teaching, demonstrate principles, and serve as a bank of resources for students and my enabling my research. I think I am a masterly teacher as I am thorough and rigorous with high expectations, yet make students learn for themselves to empower themselves to be successful in their learning.

I am a fellow of the Higher Education Academy and that means I have demonstrated a depth of skill and innovative practices in educating students. I have also taught and examined across countries and institutions and at all levels from batchelor’s to doctoral level.

As a boy I loved trying to understand how and what makes the simplest things 'tick'. In my research I love understanding how things work, I take a ‘systems approach’ as a physicist and chemist and therefore, want to know what they are made of and how they might be measured or improved on. Lecture topics generally cover means of process, material or molecule characterisation, and also cover mechanism of action, constitution and aspects of industrial fabrication.

My research interests

I have a longstanding interest in nanoscience, nanotechnology and nanophysics, soft-matter self-assemblies and coarse dispersions, including colloidal drug delivery systems and the surface adsorption of functionalising polymers. I study vaccine and particulate drug delivery systems in considerable depth. I work routinely with biosurfactants (such as proteins and peptides or gums), natural polymers, sustainable materials and synthetically modified materials.

I am interested in recycling and re-exploitation of spent and soiled or spent materials or polluted environments. I work with simple and complex foams and thin liquid films (foam lamellae). These structures relate to the quasi-2D-architectures created for a range of purposes; as means of sensing, synthesis and in their own right, to study processes such as statistical mechanics and energetics. As a nanotechnologist I also work in the field of miniaturised analytical systems – microfluidics, microarrays, sensors, diagnostic systems, and biosensors. I work in the context of product and process design and investigations associated with engineering and manufacturing process modelling. I work with the mechanics and rheology of a range of materials.

I am interested in 'invention' and equipment fabrication and design. I am fascinated by physical and engineering applications of mesophase materials (liquid crystals), coarse and colloidal dispersions, and complex fluids, such as ionic liquids, thermotropic materials, gels and emulsions.

Research activity

Current research projects:

  • Nicotine replacement therapy and drug delivery systems
  • Flexographic printing and photo-reactive polymers
  • Recycling and re-assignment of waste absorbent cotton materials
  • Physics of droplet impact, spreading and wetting
  • Nanoparticle and polymer drug delivery systems
  • Drug stability and formulation
  • Photo-dynamic nanoparticle therapy for cancer treatment
  • Pharmaceutical, medical and food packaging
  • Food science and food process technology
  • Status indicating medical device materials
  • Surfactant and detergent cleaning systems
  • Environmentally responsive encapsulated metal nanoparticles for sensor use
  • Complex fluids, ionic liquids and liquid crystals
  • Cryogels and composite insulating materials
  • Methods of assessment and evaluation in the sciences
  • Chemistry and physics educational tools

Previous research projects:

  • Enhancement of solubility in solid dispersions of drugs
  • Surface functionalisation of latex nanobeads
  • Plasma treatment of plastics for surface functionalisation
  • Flax and hemp materials and their non-food use
  • Nanomaterials in composite polymer materials
  • Microemulsions for drug delivery
  • Applications of coarse dispersions and complex fluids
  • Thin liquid films and foams
  • Wetting transitions and thin liquid films
  • Surface adsorption of polymers and proteins
  • Characterisation and identification of food authenticity
  • Theological systems for the study of surface adsorbed materials
  • Liposomal encapsulation of solids and therapeutics
  • Food gel and dispersion characterisation
  • Food preservation chemistry and processing
  • Silver catalysts for disinfection and catalysis
  • Foam films as models of cell membranes
  • Droplet spreading mechanisms
  • Food antioxidants and polyphenol chemistry
  • Formulation of curcumin and insect protein
  • Carbon nanomaterials and fluorescence applications
  • Micelles in reactors for metal recovery
  • Encapsulation of cytotoxic drugs in micelles and emulsions
  • Learning methodologies in chemistry
  • Miniature and developmental analytical systems

Research Centres and Groups

  • Chemistry research group
  • Biomaterials and medical devices research group

Social media

Contact me

Dr Dipak Sarker
Principal Lecturer in Pharmaceutics
Assistant Course Leader MPharm Programme

School of Pharmacy and Biomolecular Sciences
91¶¶Òõ
Cockcroft Building (Office: C331)
Moulsecoomb Science Campus
Lewes Road
91¶¶Òõ
BN2 4GJ, UK

Tel (Office) - +44 (0) 1273 641779
Fax - +44 (0) 1273 642674

Email: D.K.Sarker@brighton.ac.uk

Biography

I started off my academic life as a chemist and chemical engineer and engineer, before completing a PhD in physics in 1995. After several years of post-doctoral and lecturing work at universities and research institutes in France and Germany I took up a position in the School of Pharmacy and Biomolecular Sciences at the 91¶¶Òõ. My academic activities at 91¶¶Òõ cover aspects of pharmaceutical formulation and processing, physics, physical chemistry, chemical and pharmaceutical analysis and specifically areas of polymer, surface and colloid science expertise (nanotechnology) developed during doctoral and post-doctoral training. After graduation and during post-doctoral work I worked for the Swiss pharmaceutical company, Hoffman-La Roche as a chemist and the renowned pharmaceutical giant GlaxoSmithKline as a validation and quality assurance expert.

Research output

Full Books

Sarker, D.K (2008) Quality Systems and Controls for Pharmaceuticals, John Wiley and Sons, Chichester. pp. 1-182. ISBN 978-0-470-05692-9 (hb); 978-0-470-05693-6 (pb);

Sarker, Dipak (2013) Wiley-Blackwell, Chichester, UK. ISBN 9780470976838

Research Presentations

  • Howbrook et al. PCR Conference, London, January 2002
  • Sarker. British Pharmaceutical Conference, Manchester, September 2002
  • Naseem et al. British Pharmaceutical Conference, Manchester, September 2002
  • van der Valk et al. Biochips Conference, Birmingham, September 2003
  • Naseem et al. AAPS Conference, Salt Lake City, October 2003
  • van der Valk et al. QPCR Symposium, Munich, March 2004

Consultancy

  • Smpl Innovations GmbH (design organisation)
  • Graphic Supplies (UK) Ltd (commercial printing technology)
  • Cryocube (cryogenic storage of biological samples)
  • Medisort (sanitary product disposal and recycling)
  • Biofrontera AG (micellar and colloidal drug delivery systems)
  • Wiley-Blackwell Publishing
  • Food Unwrapped, Channel 4 Television
  • Curcumin nanoparticle formulation. Dr Tu Duong & Vietnamese Academy of Sciences

PhD students

 
NameThesis
Gennaro Dichello (2012-present) Targeting of brain tumours with photo-dynamic therapy using liposomes and encapsulated metal nanoparticles
Kais Shaban (2014-present) Levothyroxine drug stability and formulation in fast-dissolving oral films
Shaimaa Shakargi (2014-present) Synthesis and therapeutic use of environmentally-sensitive polymeric micelles for drug delivery
Cristina Boscariol (2015-present) The physics of impacting droplets on model solid surfaces 
Previous PhD student
Evgeniya Seliverstova (2014) Energy transfer mechanisms and the photo-optical effects of fluorophore-conjugated graphene
Carla Di Mattia (2009) Photo-oxidative changes in protein-stabilised olive oil emulsions 
Georgi Georgiev (2008) Phase transitions in striated foam films as models of cells membranes 
Othman Al-Hanbali (2008) A novel assay for block co-polymer non-ionic surfactants used in nanoparticle surface engineering 
Atia Naseem (2003) Approaches to enhancing the dissolution rate of poorly soluble drugs 

Roles

Memberships

  • Institute of Food Science and Technology
  • Royal Society of Chemistry, various subject groups
  • Institute of Nanotechnology
  • RPSGB, Academic Pharmacy Group
  • 91¶¶Òõ memberships – Academic Standards Committee, validation panelist, sustainable development representative
  • Pharmacy and Biomolecular Sciences Research Ethics Committee
  • Approved post-graduate supervisor register

Editorships

  • Section Editor: Current Drug Delivery Technologies
  • Associate Editor: Current Nanomedicine

Editorial boards

  • Recent Patents on Drug Delivery and Formulation
  • International Journal of  Innovation in Science and Mathematics Education
  • Open Colloid Science Journal
  • Advanced Materials Reviews
  • Advanced Materials Letters
  • Asian Journal of Pharmaceutics
  • Inventi Rapid-Impact: Pharm Tech
  • Khimiya (Chemistry)
  • Journal of Modern Medicinal Chemistry
  • Journal of the Chinese Advanced Materials Society
  • Recent Patents on Engineering
  • ISRN Journal of Chemistry: Medicinal Chemistry
  •  International Journal of Information System and Management Research

Reviewer

RSC Chem Comm, RSC Advances, International Journal of Pharmaceutics, Soft Matter, Langmuir, DDT, Chemical Engineering Journal, Colloids and Surfaces, Macromolecules, Cancer Letters, European Biophysics Journal, Biophysical Chemistry, International Journal of Nanomedicine, Journal of Controlled Release, RSC Dalton Transactions, Chronicles of Pharmacy, RSC Journal of Materials Chemistry B, RSC Analytical Methods.

John Wiley (scientific books), etc.,

Research council reviewing

  1. EPSRC: Physics/Applied Mathematics
  2. BBSRC: Food, Engineering, Biotechnology and Biological Sciences
  3. MRC: Therapeutics and Drug Delivery

Organising committees

  • Conference Committee - 2nd International Conference on Advanced Materials 2013 (China)
  • Organising committee: International Union of Advanced Materials - Academic Committee Member 2011, Hong Kong
  • Advisory board: Advanced Materials World Congress (AM 2013, organized by the International Association of Advanced Materials), Turkey, September 2013
  • International Advisory Board 2nd World Conference on Science and Mathematics Education , 15-17 Oct 2015, Cyprus

Awards

  • Sosabowski, M.H., Piatt, R., Sarker, D.K. (2003) “Young Chemists’ Learning Project,” 91¶¶Òõ Innovation Awards 2003 - Prize Winner, Business Services, University 91¶¶Òõ
  • Dipak K. Sarker, Featured chemist: RSC News Chemistry World, Feb 2005, p12
  • Chair of the Downland Section of RSC from (Sussex, Surrey, Hamphire, Kent) 2005-2008
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